Assays - Phenytoin

Comparative bioavailability of several Phenytoin preparations marketed in Austria

Author: V. Nitsche, H.J. Mascher, H. Schütz
Publisher: Int. J. Clin. Pharmacol., Ther. and Toxicol. 22 (1984), 104-107

In a multiple, randomized crossover study, plasma concentrations were determined following oral single-dose administration of various phenytoin preparations. With the exception of one formulations tested (p ≤ 0.01), no statistically significant difference was found among the remaining preparations.